afamelanotide( —— )

Catalog No. M20799 CAS No. 1566590-77-9

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Datasheet

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Product Name

afamelanotide
Note

Research use only, not for human use.
Brief Description

Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist used to for Erythropoietic Protoporphyria.
Description

Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist used to for Erythropoietic Protoporphyria.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Metabolic Disease
Indication

erythropoietic protoporphyria?

CAS Number

1566590-77-9
Formula Weight

1706.9
Molecular Formula

C80H115N21O21
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(O)=O.CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
Chemical Name

——

1.Langendonk J G Balwani M Anderson K E et al. Afamelanotide for Erythropoietic Protoporphyria[J]. New England Journal of Medicine 2015 373(1):48-59.

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