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TAS-102
CAS No. 733030-01-8
TAS-102( TAS102, TAS-102, TAS 102, Trifluridine/tipiracil hydrochloride )
Catalog No. M15805 CAS No. 733030-01-8
TAS-102 is an investigational drug candidate for metastatic colorectal Y. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 2MG | 31 | In Stock |
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| 5MG | 49 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 151 | In Stock |
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| 50MG | 245 | In Stock |
|
| 100MG | 369 | In Stock |
|
| 200MG | 556 | In Stock |
|
| 500MG | 870 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTAS-102
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NoteResearch use only, not for human use.
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Brief DescriptionTAS-102 is an investigational drug candidate for metastatic colorectal Y. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
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DescriptionTAS-102 is an investigational drug candidate for metastatic colorectal Y. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
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In Vitro——
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In VivoAnimal Model:Male nude mice bearing KM12C, KM12C/5-FU, DLD-1, DLD-1/5-FU, and SC-2 cells Dosage:150 mg/kg/day Administration:p.o.; twice a day for 14 daysResult:Prevented body weight loss and reduced the relative tumor volume in colorectal cancer and gastric cancer mice models.
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SynonymsTAS102, TAS-102, TAS 102, Trifluridine/tipiracil hydrochloride
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number733030-01-8
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Formula Weight575.32
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Molecular FormulaC19H23Cl2F3N6O7
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESO=C1NC(C(C(F)(F)F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O.O=C3NC(C(Cl)=C(CN4C(CCC4)=N)N3)=O.[H]Cl
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Chemical Name4-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidin-2(1H)-one compound with 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4-diol (1:1) hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nukatsuka M, et al. anticancer Res. 2015 Sep;35(9):4605-15.
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