Clocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells. It also could rescue impairments of mitochondrial motility and neurite outgrowth.

2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-?oB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity.