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AKR1C3-IN-1
CAS No. 327092-81-9
AKR1C3-IN-1( —— )
Catalog No. M20737 CAS No. 327092-81-9
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 46 | In Stock |
|
| 25MG | 83 | In Stock |
|
| 50MG | 147 | In Stock |
|
| 100MG | 239 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAKR1C3-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionAKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
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DescriptionAKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
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In VitroAKR1C3-IN-1 shows less potent activities with 20.3±3.8 μM against AKR1C1 and >30 μM against AKR1C2 and AKR1C4. AKR1C3-IN-1 inhibits AKR1C3 activity (inhibiting PR-104H formation) with an IC50 of 0.027±0.002 μM.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetNADPH
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RecptorAKR1C3
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Research Area——
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Indication——
Chemical Information
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CAS Number327092-81-9
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Formula Weight317.36
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Molecular FormulaC16H15NO4S
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (315.10 mM)
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SMILESOC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccccc2C1
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Chemical Name3-(34-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jamieson S M F Brooke D G Heinrich D et al. 3-(34-Dihydroisoquinolin-2(1 H )-ylsulfonyl)benzoic Acids: Highly Potent and Selective Inhibitors of the Type 5 17-β-Hydroxysteroid Dehydrogenase AKR1C3[J]. Journal of Medicinal Chemistry 2012 55(17):7746-7758.
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