Cart
sales@molnova.com
DNQX
CAS No. 2379-57-9
DNQX( FG 9041 )
Catalog No. M20669 CAS No. 2379-57-9
DNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 25MG | 48 | In Stock |
|
| 50MG | 76 | In Stock |
|
| 100MG | 109 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDNQX
-
NoteResearch use only, not for human use.
-
Brief DescriptionDNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).
-
DescriptionDNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).
-
In VitroDNQX selectively depolarizes thalamic reticular nucleus (TRN) neurons.
-
In VivoDNQX, a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex.
-
SynonymsFG 9041
-
PathwayNeuroscience
-
TargetGluR
-
RecptorAMPA
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2379-57-9
-
Formula Weight252.14
-
Molecular FormulaC8H4N4O6
-
Purity>98% (HPLC)
-
SolubilityDMSO:35 mg/mL (138.81 mM)
-
SMILES[O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1[N+]([O-])=O
-
Chemical Name67-Dinitroquinoxaline-23(1H4H)-dione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Muller D Joly M Lynch G . Contributions of quisqualate and NMDA receptors to the induction and expression of LTP[J]. Science 1988 242(4886):1694-1697.
molnova catalog
related products
-
AMN 082 dihydrochlor...
AMN 082 dihydrochloride is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
-
VU0155094
ML397 is a positive allosteric modulator with differential activity at the various group III mGluRs.
-
FPTQ
FPTQ is an antagonist of mGluR1.FPTQ is a synthetic isoquinoline derivative.
