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DNQX
CAS No. 2379-57-9
DNQX( FG 9041 )
Catalog No. M20669 CAS No. 2379-57-9
DNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 25MG | 48 | In Stock |
|
| 50MG | 76 | In Stock |
|
| 100MG | 109 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDNQX
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NoteResearch use only, not for human use.
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Brief DescriptionDNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).
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DescriptionDNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).
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In VitroDNQX selectively depolarizes thalamic reticular nucleus (TRN) neurons.
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In VivoDNQX, a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex.
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SynonymsFG 9041
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PathwayNeuroscience
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TargetGluR
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RecptorAMPA
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Research Area——
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Indication——
Chemical Information
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CAS Number2379-57-9
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Formula Weight252.14
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Molecular FormulaC8H4N4O6
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Purity>98% (HPLC)
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SolubilityDMSO:35 mg/mL (138.81 mM)
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SMILES[O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1[N+]([O-])=O
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Chemical Name67-Dinitroquinoxaline-23(1H4H)-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Muller D Joly M Lynch G . Contributions of quisqualate and NMDA receptors to the induction and expression of LTP[J]. Science 1988 242(4886):1694-1697.
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