bruceine B

CAS No. 25514-29-8

bruceine B( —— )

Catalog No. M20422 CAS No. 25514-29-8

Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 297 In Stock
10MG 485 In Stock
25MG 772 In Stock
50MG 1042 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    bruceine B
  • Note
    Research use only, not for human use.
  • Brief Description
    Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.
  • Description
    Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.
  • In Vitro
    Bruceine B exhibits an IC50 of 10 nM for antimalarial activity.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    25514-29-8
  • Formula Weight
    480.5
  • Molecular Formula
    C23H28O11
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]12[C@@H](OC(C)=O)C(=O)O[C@]3([H])C[C@@]4([H])C(C)=C(O)C(=O)C[C@]4(C)[C@@]4([H])[C@@H](O)[C@H](O)[C@]1(OC[C@@]234)C(=O)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Utoguchi N Nakata T Cheng H H et al. Bruceine B A Potent Inhibitor of Leukocyte-Endothelial Cell Adhesion[J]. Inflammation 1997 21(2):223-233.
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