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5-Benzylidene-3-ethyl rhodanine

CAS No. 18331-34-5

5-Benzylidene-3-ethyl rhodanine( —— )

Catalog No. M20405 CAS No. 18331-34-5

5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 51 In Stock
2MG 29 In Stock
5MG 46 In Stock
10MG 77 In Stock
25MG 140 In Stock
50MG 207 In Stock
100MG 313 In Stock
200MG 458 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    5-Benzylidene-3-ethyl rhodanine
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
  • Description
    5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
  • In Vitro
    BTR-1 (10, 50, 100, and 250 μM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 μM at 48 and 72 h, respectively.Cell Viability AssayCell Line:T-cell leukemic cell lines Concentration:10, 50, 100, and 250 μM Incubation Time:5 days Result:Induced cytotoxicity in human leukemic cells in a dose-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    18331-34-5
  • Formula Weight
    249.35
  • Molecular Formula
    C12H11NOS2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25 mg/mL (100.26 mM)
  • SMILES
    CCN1C(=S)S\C(C1=O)=C/c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Moorthy B T Ravi S Srivastava M et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis[J]. Bioorganic and Medicinal Chemistry Letters 2010 20(21):6297-6301.
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