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Aurora Kinase Inhibitor III
CAS No. 879127-16-9
Aurora Kinase Inhibitor III( —— )
Catalog No. M20361 CAS No. 879127-16-9
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX BTK IGF-1R c-Src TRKB SYK and EGFR.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
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| 2MG | 91 | In Stock |
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| 5MG | 155 | In Stock |
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| 10MG | 250 | In Stock |
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| 25MG | 424 | In Stock |
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| 50MG | 600 | In Stock |
|
| 100MG | 824 | In Stock |
|
| 200MG | 1135 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAurora Kinase Inhibitor III
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NoteResearch use only, not for human use.
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Brief DescriptionAurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX BTK IGF-1R c-Src TRKB SYK and EGFR.
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DescriptionAurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX BTK IGF-1R c-Src TRKB SYK and EGFR.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetAurora Kinase
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RecptorAurora A
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Research Area——
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Indication——
Chemical Information
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CAS Number879127-16-9
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Formula Weight413.4
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Molecular FormulaC21H18F3N5O?
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (120.9 mM)
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SMILESFC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1
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Chemical NameN-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang Q Liu Y Gao F et al. Discovery of EGFR Selective 46-Disubstituted Pyrimidines from a Combinatorial Kinase-Directed Heterocycle Library[J]. Journal of the American Chemical Society 2006 128(7):2182-2183.
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