Cart
sales@molnova.com
CGP71683 hydrochloride
CAS No. 192322-50-2
CGP71683 hydrochloride( CGP71683A )
Catalog No. M20256 CAS No. 192322-50-2
CGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 113 | In Stock |
|
| 5MG | 102 | In Stock |
|
| 10MG | 154 | In Stock |
|
| 25MG | 256 | In Stock |
|
| 50MG | 361 | In Stock |
|
| 100MG | 528 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCGP71683 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionCGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
-
DescriptionCGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
-
In VitroCGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
-
In VivoCGP71683 (15 nmol/rat, icv, twice daily) shows anorexigenic effect, reducing food intake and bady weight of fed rats. CGP71683 causes 3-times higher serum total T4 and 37% increase in free T4 in the fasted rats than in the fasted controls rats.
-
SynonymsCGP71683A
-
PathwayGPCR/G Protein
-
TargetNeuropeptide Y Receptor
-
RecptorY5 receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number192322-50-2
-
Formula Weight512.07
-
Molecular FormulaC26H30ClN5O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 120 mg/mL (234.34 mM);Water: 10 mg/mL (19.53 mM)
-
SMILESCl.Nc1nc(NC[C@H]2CC[C@H](CNS(=O)(=O)c3cccc4ccccc34)CC2)nc2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Pancreatic Polypepti...
Agonist at Y4 neuropeptide Y receptors.
-
[cPP1-7,NPY19-23,Ala...
Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
-
Neuropeptide Y (22-3...
Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the mammalian central nervous system, which consists of the brain and spinal cord. It is secreted alongside other neurotransmitters such as GABA and glutamate.
