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Prostaglandin E2 (PGE2)
CAS No. 363-24-6
Prostaglandin E2 (PGE2)( Dinoprostone | Prostaglandin E2 | PGE2 )
Catalog No. M19799 CAS No. 363-24-6
Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 2MG | 40 | In Stock |
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| 5MG | 62 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 170 | In Stock |
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| 50MG | 238 | In Stock |
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| 100MG | 344 | In Stock |
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| 200MG | 505 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameProstaglandin E2 (PGE2)
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NoteResearch use only, not for human use.
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Brief DescriptionProstaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.
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DescriptionProstaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.(In Vitro):Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
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In VitroProstaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
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In Vivo——
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SynonymsDinoprostone | Prostaglandin E2 | PGE2
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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RecptorEP2?Receptor|Human Endogenous Metabolite
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Research AreaOthers
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IndicationLabour induction
Chemical Information
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CAS Number363-24-6
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Formula Weight352.47
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Molecular FormulaC20H32O5
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Purity>98% (HPLC)
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SolubilityDMSO:35.3 mg/mL(100 mM)
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SMILESCCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
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Chemical Name(Z)-7-((1R2R3R)-3-hydroxy-2-((SE)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Fernandez-Repollet E et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70.
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