Prostaglandin E2 (PGE2)

CAS No. 363-24-6

Prostaglandin E2 (PGE2)( Dinoprostone | Prostaglandin E2 | PGE2 )

Catalog No. M19799 CAS No. 363-24-6

Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 61 In Stock
10MG 85 In Stock
25MG 177 In Stock
50MG 341 In Stock
100MG 530 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Prostaglandin E2 (PGE2)
  • Note
    Research use only, not for human use.
  • Brief Description
    Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.
  • Description
    Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.(In Vitro):Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
  • In Vitro
    Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
  • In Vivo
    ——
  • Synonyms
    Dinoprostone | Prostaglandin E2 | PGE2
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    EP2?Receptor|Human Endogenous Metabolite
  • Research Area
    Others
  • Indication
    Labour induction

Chemical Information

  • CAS Number
    363-24-6
  • Formula Weight
    352.47
  • Molecular Formula
    C20H32O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:35.3 mg/mL(100 mM)
  • SMILES
    CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
  • Chemical Name
    (Z)-7-((1R2R3R)-3-hydroxy-2-((SE)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fernandez-Repollet E et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70.
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