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L-Kynurenine
CAS No. 2922-83-0
L-Kynurenine( (S)-Kynurenine )
Catalog No. M19725 CAS No. 2922-83-0
L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 25MG | 29 | In Stock |
|
| 50MG | 37 | In Stock |
|
| 100MG | 52 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameL-Kynurenine
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NoteResearch use only, not for human use.
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Brief DescriptionL-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
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DescriptionL-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
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In Vitro——
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In Vivo——
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Synonyms(S)-Kynurenine
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite|AhR
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Research Area——
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Indication——
Chemical Information
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CAS Number2922-83-0
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Formula Weight208.21
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Molecular FormulaC10H12N2O3
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL
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SMILESN[C@@H](CC(=O)c1ccccc1N)C(O)=O
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Chemical Name(S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kolho K L Pessia A Jaakkola T et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis 2017 11(3):321-334.
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