L-Kynurenine

CAS No. 2922-83-0

L-Kynurenine( (S)-Kynurenine )

Catalog No. M19725 CAS No. 2922-83-0

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
25MG 29 In Stock
50MG 37 In Stock
100MG 52 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    L-Kynurenine
  • Note
    Research use only, not for human use.
  • Brief Description
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
  • Description
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (S)-Kynurenine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite|AhR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2922-83-0
  • Formula Weight
    208.21
  • Molecular Formula
    C10H12N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL
  • SMILES
    N[C@@H](CC(=O)c1ccccc1N)C(O)=O
  • Chemical Name
    (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kolho K L Pessia A Jaakkola T et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis 2017 11(3):321-334.
molnova catalog
related products
  • Pseudouridine

    Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.

  • Succinyl-Coenzyme A ...

    Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodium salt) is involved in a variety of metabolic reactions in living organisms.

  • Campesterol

    Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory effect, it inhibits several pro-inflammatory and matrix degradation mediators typically involved in osteoarthritis- induced cartilage degradation, also sometimes used to treat some specific prostate conditions.