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PU-H71

CAS No. 873436-91-0

PU-H71( NSC 750424 )

Catalog No. M19535 CAS No. 873436-91-0

PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM. Phase 1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	78	In Stock
2MG	33	In Stock
5MG	52	In Stock
10MG	83	In Stock
25MG	132	In Stock
50MG	184	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PU-H71
Note

Research use only, not for human use.
Brief Description

PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM. Phase 1.
Description

PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM. Phase 1.
In Vitro

——
In Vivo

——
Synonyms

NSC 750424
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSP90
Research Area

Cancer
Indication

Breast Cancer; Myelofibrosis; Pancreatic Cancer

Chemical Information

CAS Number

873436-91-0
Formula Weight

512.37
Molecular Formula

C18H21IN6O2S
Purity

>98% (HPLC)
Solubility

Ethanol: 100 mg/mL (195.17 mM);DMSO: 100 mg/mL (195.17 mM);Water: 34 mg/mL (66.35 mM) warmed
SMILES

CC(C)NCCCN1C(SC2=CC3=C(OCO3)C=C2I)=NC2=C(N)N=CN=C12 |c:18212326t:101228|
Chemical Name

8-((6-iodobenzo[d][13]dioxol-5-yl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Caldas-Lopes E et al. Proc Natl Acad Sci U S A 2009 106(20) 8368-8373.

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