AK778

CAS No. 328906-67-8

AK778( AK 778 | Col001 )

Catalog No. M14077 CAS No. 328906-67-8

AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    AK778
  • Note
    Research use only, not for human use.
  • Brief Description
    AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen.
  • Description
    AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AK 778 | Col001
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    328906-67-8
  • Formula Weight
    462.509
  • Molecular Formula
    C28H22N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-(((5-(1H-benzo[d]imidazol-2-yl)-2-methylphenyl)imino)methyl)-4-benzyl-6-nitrophenol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085.
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