Cart
sales@molnova.com
Quinolinic acid
CAS No. 89-00-9
Quinolinic acid( —— )
Catalog No. M19233 CAS No. 89-00-9
Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 28 | In Stock |
|
Biological Information
-
Product NameQuinolinic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionQuinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
-
DescriptionQuinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
-
In VitroQuinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells. Cell Viability Assay Cell Line:N18D3 cells, hybrid neuronal cell line obtained by fusion of dorsal root ganglions isolated from 4-week-old Balb/C mouse with the mouse neuroblastoma N18TG2 cells Concentration:0, 10, 20, 30, 40, 50 mM Incubation Time:24 hoursResult:There was a corresponding decrease in the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorNMDA receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number89-00-9
-
Formula Weight173.17
-
Molecular FormulaC10H7NO2
-
Purity>98% (HPLC)
-
SolubilityDMSO : 33.33 mg/mL 199.44 mM
-
SMILESOC(=O)c1cccnc1C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lugohuitrón R, et al. Quinolinic acid: an endogenous neurotoxin with multiple targets.[J]. Oxidative Medicine and Cellular Longevity,2013,(2013-9-5), 2013, 2013:104024.
molnova catalog
related products
-
debutylbupivacaine
It is the intermediate of Ropivacaine Hydrochloride and Bupivacain.
-
Methyl retinoate
Methyl retinoate (Retinoic acid, methyl ester) induces aseptic inflammation at the site of administration in in vivo experiments, which causes an increase in the number of leukocytes in the blood and a decrease in the levels of red blood cells and Hb.Methyl retinoate promotes spontaneous leukemia.Methyl retinoate can be Used in the treatment of gastric hypertrophy and ulcers due to vitamin A deficiency.
-
N-Acetyl-L-methionin...
N-Acetyl-L-methionine is an L-methionine derivative that is nutritionally and metabolically equivalent to L-methionine. It is a superior ROS scavenger.
