Endosidin-2

CAS No. 1839524-44-5

Endosidin-2( —— )

Catalog No. M34902 CAS No. 1839524-44-5

Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 49 In Stock
5MG 45 In Stock
10MG 85 In Stock
25MG 187 In Stock
50MG 299 In Stock
100MG 500 In Stock
200MG Get Quote In Stock
500MG 1070 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Endosidin-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Endosidin-2 is an exocyst inhibitor, a cell-permeable benzylidene benzoylhydrazine, that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 μM, EXO70A1).
  • Description
    Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1839524-44-5
  • Formula Weight
    414.17
  • Molecular Formula
    C15H12FIN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (241.45 mM; Ultrasonic )
  • SMILES
    COC1=CC(\C=N\NC(=O)C2=CC=CC(F)=C2)=CC(I)=C1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang C, et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50. ?
molnova catalog
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