Dehydromiltirone( —— )

Catalog No. M30947 CAS No. 116064-77-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Dehydromiltirone
Note

Research use only, not for human use.
Brief Description

Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.
Description

Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.
In Vitro

Western Blot Analysis Cell Line:Kupffer cells Concentration:100?μg/mL Incubation Time:For 24?h Result:Significantly decreased p38 and p-p38 levels, NF-κBp65, IκB, andc-fos protein levels.
In Vivo

Animal Model:Rat model of acute liver injury Dosage:50 mg/kg, 100 mg/kg, and 200?mg/kg Administration:p.o.; daily; for five consecutive days Result:Protected liver from CCl4-induced damage.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

Calculator

molnova catalog