Gadopentetate dimeglumine

CAS No. 86050-77-3

Gadopentetate dimeglumine( SH-L-451A | Gadopentetic acid dimeglumine salt )

Catalog No. M19187 CAS No. 86050-77-3

Gadopentetate dimeglumine, an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Gadopentetate dimeglumine
  • Note
    Research use only, not for human use.
  • Brief Description
    Gadopentetate dimeglumine, an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.
  • Description
    Gadopentetate dimeglumine, an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.(In Vitro):Gadobenate dimeglumine-enhanced MRI significantly improves cancer detection compared to gadopentetate dimeglumine-enhanced MRI, mammography, and ultrasound in a selected group of patients undergoing breast MRI for preoperative staging or because of inconclusive findings at conventional imaging. Interstitial MR lymphography with gadopentetate dimeglumine (Gd-DTPA) or gadoxetate disodium (Gd-EOB-DTPA) allows clear visualization of the lymphatic pathway in healthy mice, and no significant difference is found between the two agents. Their rapid kinetics limits the imaging timing window, however, facilitates repeated assessment in a single imaging session. Direct visualization of spilled gastrointestinal gadopentetate dimeglumine helps discriminate ischemic from control rats in this model.
  • In Vitro
    Gadobenate dimeglumine-enhanced MRI significantly improves cancer detection compared to gadopentetate dimeglumine-enhanced MRI, mammography, and ultrasound in a selected group of patients undergoing breast MRI for preoperative staging or because of inconclusive findings at conventional imaging. Interstitial MR lymphography with gadopentetate dimeglumine (Gd-DTPA) or gadoxetate disodium (Gd-EOB-DTPA) allows clear visualization of the lymphatic pathway in healthy mice, and no significant difference is found between the two agents. Their rapid kinetics limits the imaging timing window, however, facilitates repeated assessment in a single imaging session. Direct visualization of spilled gastrointestinal gadopentetate dimeglumine helps discriminate ischemic from control rats in this model.
  • In Vivo
    ——
  • Synonyms
    SH-L-451A | Gadopentetic acid dimeglumine salt
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Wnt/beta/catenin
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    86050-77-3
  • Formula Weight
    938
  • Molecular Formula
    C14H20GdN3O10.2C7H17NO5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 5 mg/mL 5.33 mM
  • SMILES
    [Gd+3].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sheng F, et al. Interstitial MR lymphography in mice with gadopentetate dimeglumine and gadoxetate disodium. J Magn Reson Imaging. 2011 Feb;33(2):490-7.
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