Danshensu

CAS No. 76822-21-4

Danshensu( Dan shen suan A | Salvianic acid A )

Catalog No. M19093 CAS No. 76822-21-4

Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 48 In Stock
25MG 75 In Stock
50MG 100 In Stock
100MG 151 In Stock
200MG Get Quote In Stock
500MG 352 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Danshensu
  • Note
    Research use only, not for human use.
  • Brief Description
    Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.
  • Description
    Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.
  • In Vitro
    Cell Migration Assay Cell Line:FaDu and Ca9-22 cells Concentration:25, 50, and 100 μM Incubation Time:24 h Result:At higher concentrations (50 and 100 μM) caused significant reduction in migration and invasion of both FaDu and Ca9-22 cells.Western Blot Analysis Cell Line:FaDu and Ca9-22 cells Concentration:25, 50, and 100 μM Incubation Time:24 h Result:Phosphorylation of ERK reduced dose-dependently after 24 h in FaDu cell. Caused significant reduction in p38 phosphorylation.
  • In Vivo
    Animal Model:Adult BALB/c mice (male, 6-8 weeks, 20±2?g)Dosage:25, 50, 100?mg/kg Administration:Oral administration (daily for 7 continuous days) or i.v. (once) Result:Could prevent SARS-CoV-2 S protein-induced acute lung inflammation. Ameliorated inflammatory cytokines in serum and lung tissue.
  • Synonyms
    Dan shen suan A | Salvianic acid A
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    Others
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    76822-21-4
  • Formula Weight
    198.17
  • Molecular Formula
    C9H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 6.2 mg/mL 31.29 mM
  • SMILES
    c1cc(c(cc1C[C@H](C(=O)O)O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. YG Cao, et al.Br J Pharmacol. 2009 Jun; 157(3): 482–490.
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