Gentiannine

CAS No. 439-89-4

Gentiannine( ——— )

Catalog No. M38798 CAS No. 439-89-4

Gentianine, an active metabolite of Swertiamarin, has anti-diabetic effect and anti-inflammatory property.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Gentiannine
  • Note
    Research use only, not for human use.
  • Brief Description
    Gentianine, an active metabolite of Swertiamarin, has anti-diabetic effect and anti-inflammatory property.
  • Description
    Gentianine has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, and diuretic actions, it could be developed as a safe antihypertensive drug.
  • In Vitro
    ———
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    PPAR;GLUT;TNF-α
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    439-89-4
  • Formula Weight
    175.18
  • Molecular Formula
    C10H9NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL (285.42 mM; ultraphonic )
  • SMILES
    C=CC1=CN=CC2=C1CCOC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vaidya H, et al. Anti-diabetic activity of swertiamarin is due to an active metabolite, gentianine, that upregulates PPAR-γ gene expression in 3T3-L1 cells. Phytother Res. 2013 Apr;27(4):624-7.?
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