Ferrous Bisglycinate

Research use only, not for human use.

Ferrous Bisglycinate is used in the fortification of infant formulations and foods.

Ferrous Bisglycinate is used in the fortification of infant formulations and foods.(In Vitro):Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability.Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells.(In Vivo):Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice.

Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability.Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells. Cell Viability Assay Cell Line:Caco-2 cells Concentration:0, 25, 50, 100, 200 μM Incubation Time:2 hours Result:Did not affect the viability of wild-type and divalent metal transporter 1 (DMT1) knockout Caco-2 cells.Western Blot Analysis Cell Line:Caco-2 cells Concentration:25 μM Incubation Time:2 hours Result:Increased ferritin content and decreased DMT1 expression levels significantly in the wild-type cells.

Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice. Animal Model:Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)Dosage:500 mg/kg iron Administration:P.o. (add to the diet) for 10 daysResult:Had the best survival rates (100%).

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Metabolic Enzyme/Protease

IDO

ER|PR

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20150-34-9

203.96

C4H8FeN2O4

>98% (HPLC)

In Vitro:?0.1 M HCL : 2 mg/mL (9.90 mM)

[Fe++].NCC([O-])=O.NCC([O-])=O

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(-20℃)

With Ice Pack

≥ 2 years