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O4I1
CAS No. 175135-47-4
O4I1( O4I1 | O4I-1 | O4I 1 )
Catalog No. M18127 CAS No. 175135-47-4
O4I1 is an effective Oct3/4 inducer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 25MG | 34 | In Stock |
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| 50MG | 51 | In Stock |
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| 100MG | 89 | In Stock |
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| 200MG | 155 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameO4I1
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NoteResearch use only, not for human use.
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Brief DescriptionO4I1 is an effective Oct3/4 inducer.
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DescriptionO4I1 is a potent inducer of Oct3/4. O4I1 enhanced Oct3/4 expression. O4I1 not only promoted expression and stabilization of Oct3/4 but also enhanced its transcriptional activity in diverse human somatic cells, implying the possible benefit from using this class of compounds in regenerative medicine. Reprogramming somatic cells into induced-pluripotent cells (iPSCs) provides new access to all somatic cell types for clinical application without any ethical controversy arising from the use of embryonic stem cells (ESCs).
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In Vitro——
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In Vivo——
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SynonymsO4I1 | O4I-1 | O4I 1
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PathwayAutophagy
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TargetAutophagy
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RecptorOCT3| OCT4
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number175135-47-4
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Formula Weight253.3
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Molecular FormulaC16H15NO2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 38 mg/mL; 150.02 mM
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SMILESCOc1ccc(cc1)COc1ccc(cc1)CC#N
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Chemical Name4-[(4-Methoxyphenyl)methoxy]benzeneacetonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AUTEN-67
A small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14; at concentrations of 2, 10, and 100 uM, AUTEN-67 inhibits MTMR14 by nearly 3%, 25%, and 70%, respectively.
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Cysteamine hydrochlo...
An agent for the treatment of nephropathic cystinosis and an antioxidant; increases intracellular glutathione levels in cystinotic cells, also increases the rates of apoptosis in cystinotic cells.
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LYN-1604 2HCl 221675...
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo.
