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FPH2
CAS No. 957485-64-2
FPH2( BRD-9424 )
Catalog No. M17692 CAS No. 957485-64-2
FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 5MG | 37 | In Stock |
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| 10MG | 72 | In Stock |
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| 25MG | 180 | In Stock |
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| 50MG | 305 | In Stock |
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| 100MG | 538 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFPH2
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NoteResearch use only, not for human use.
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Brief DescriptionFPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
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DescriptionFPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
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In VitroFPH2 induces functional proliferation of hepatocytes in vitro, and thus may be useful for expanding mature human primary hepatocytes. FPH1 and FPH2 can increase in hepatocyte nuclei count and/or elevate the number of nuclei undergoing mitosis during primary screening, and these effects on hepatocytes are concentration dependent. Cells treated with FPH1 and FPH2 also maintain their liver-specific functions. Over 7 days, FPH2 induces hepatocyte doublings at a rate that is consistent with reported liver regeneration kinetics in vivo.
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In Vivo——
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SynonymsBRD-9424
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number957485-64-2
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Formula Weight353.83
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Molecular FormulaC14H16ClN5O2S
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 125 mg/mL; 353.28 mM
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SMILESClc1cc(NC(=S)Nc2cn(nc2C(=O)N)CC)c(OC)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shan J, et al. Nat Chem Biol. 2013, 9(8), 514-520.
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