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methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate
CAS No. 517870-17-6
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate( —— )
Catalog No. M24490 CAS No. 517870-17-6
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate targets MAPK.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 29 | In Stock |
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| 25MG | 51 | In Stock |
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| 50MG | 75 | In Stock |
|
| 100MG | 112 | In Stock |
|
| 200MG | 168 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Namemethyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate
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NoteResearch use only, not for human use.
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Brief Descriptionmethyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate targets MAPK.
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Descriptionmethyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate targets MAPK.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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RecptorMAPK
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Research Area——
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Indication——
Chemical Information
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CAS Number517870-17-6
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Formula Weight263.25
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Molecular FormulaC13H13NO5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCOC1=C(C=C(C=C1)C2=CC(=NO2)C(=O)OC)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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p38α inhibitor 3
p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block the effectiveness of myoblast differentiation.
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CC-99677
CC-99677 (Gamcemetinib) is a selectively targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune diseases that translates biochemical potency into cellular potency as demonstrated by potent inhibition of heat shock protein 27 (HSP1) phosphorylation in LPS-activated monocyte THP-27 cells via a nucleophilic aromatic substitution (SNAr) mechanism.
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Darizmetinib
Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration.
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