Cart
sales@molnova.com
p38α inhibitor 4
CAS No. 1262406-08-5
p38α inhibitor 4( —— )
Catalog No. M37207 CAS No. 1262406-08-5
p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 686 | In Stock |
|
| 10MG | 938 | In Stock |
|
| 25MG | 1444 | In Stock |
|
| 50MG | 1841 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Namep38α inhibitor 4
-
NoteResearch use only, not for human use.
-
Brief Descriptionp38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.
-
Descriptionp38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
Targetp38 MAPK
-
Recptorp38 MAPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1262406-08-5
-
Formula Weight347.215
-
Molecular FormulaC14H7F6N3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C1C=C(C=2C(=NNC2N1)C=3C=CC=C(C3)C(F)(F)F)C(F)(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. ACS Chem. Biol., Article ASAP
DOI: 10.1021/cb1002619
Publication Date (Web): November 23, 2010
molnova catalog
related products
-
Methyl Oleate
Methyl Oleate is an unsaturated high fatty acid ester, an important chemical raw material, widely used in the preparation of surfactants, leather additives, textile additives, as well as insecticide additives.
-
MW181 hydrochloride
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM.
-
CC-99677
CC-99677 (Gamcemetinib) is a selectively targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune diseases that translates biochemical potency into cellular potency as demonstrated by potent inhibition of heat shock protein 27 (HSP1) phosphorylation in LPS-activated monocyte THP-27 cells via a nucleophilic aromatic substitution (SNAr) mechanism.
