VAS2870

CAS No. 722456-31-7

VAS2870( VAS 2870 )

Catalog No. M17580 CAS No. 722456-31-7

VAS2870 is a NADPH oxidase (NOX) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 55 In Stock
5MG 49 In Stock
10MG 93 In Stock
25MG 180 In Stock
50MG 321 In Stock
100MG 480 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    VAS2870
  • Note
    Research use only, not for human use.
  • Brief Description
    VAS2870 is a NADPH oxidase (NOX) inhibitor.
  • Description
    VAS 2870 is a NADPH oxidase (Nox) inhibitor that enhances TGF-β-induced apoptosis of liver tumor cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VAS 2870
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    NADPH oxidase (NOX)
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    722456-31-7
  • Formula Weight
    360.4
  • Molecular Formula
    C18H12N6OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 83.3 mg/mL. 231.14 mM;
  • SMILES
    C12=C(SC3=NC4=C(C=CC=C4)O3)N=CN=C1N(CC5=CC=CC=C5)N=N2
  • Chemical Name
    7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.ten Freyhaus H, et al. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc Res. 2006 Jul 15;71(2):331-41.
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