AZ-33( AZ-33 | AZ 33 | AZ33 | LDHA Inhibitor 33 )

Catalog No. M17263 CAS No. 1370290-34-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

AZ-33
Note

Research use only, not for human use.
Brief Description

AZ-33 is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 μM.
Description

AZ-33, also known as LDHA Inhibitor 33, is a LDHA Inhibitor. Lactate dehydrogenase A (LDHA), a key enzyme involved in anaerobic glycolysis, is frequently deregulated in human malignancies.
In Vitro

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In Vivo

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Synonyms

AZ-33 | AZ 33 | AZ33 | LDHA Inhibitor 33
Pathway

Neuroscience
Target

GluR
Recptor

LDHA
Research Area

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Indication

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CAS Number

1370290-34-8
Formula Weight

497.56
Molecular Formula

C25H27N3O6S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (200.98 mM)
SMILES

O=C(O)C(C(=O)O)Cc1ccc(cc1)CCCC(=O)NCCC(=O)Nc1ccc2c(c1)sc(n2)C
Chemical Name

2-(4-(4-((3-((2-Methylbenzo[d]thiazol-6-yl)amino)-3-oxopropyl)amino)-4-oxobutyl)benzyl)malonic acid

1. Ward RA, et al.J Med Chem. 2012 Apr 12;55(7):3285-306.

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