BRD1991( BRD-1991 )

Catalog No. M17099 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

BRD1991
Note

Research use only, not for human use.
Brief Description

BRD1991 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
Description

BRD1991 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
In Vitro

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In Vivo

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Synonyms

BRD-1991
Pathway

Angiogenesis
Target

Bcl-2
Recptor

Bcl-2
Research Area

——
Indication

——

CAS Number

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Formula Weight

608.56
Molecular Formula

C33H35Cl2N3O4
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

3,5-dichloro-N-((10-(1-hydroxypropan-2-yl)-8,12-dimethyl-11-oxo-7,8,9,10,11,12-hexahydro-5H-benzo[9,10][1]oxa[5]azacycloundecino[7,8-b]indol-7-yl)methyl)-N-methylbenzamide

1. Chiang WC, et al. ACS Chem Biol. 2018 Jun 21. doi: 10.1021/acschembio.8b00421.

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