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(22E)-Ergosta-4,6,8(14),22-tetraen-3-one

CAS No. 19254-69-4

(22E)-Ergosta-4,6,8(14),22-tetraen-3-one( ——— )

Catalog No. M39405 CAS No. 19254-69-4

Ergosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

(22E)-Ergosta-4,6,8(14),22-tetraen-3-one
Note

Research use only, not for human use.
Brief Description

Ergosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum.
Description

Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment.
In Vitro

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In Vivo

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Synonyms

———
Pathway

Angiogenesis
Target

Bcl-2
Recptor

Bcl-2; p53; Caspase
Research Area

———
Indication

———

Chemical Information

CAS Number

19254-69-4
Formula Weight

392.62
Molecular Formula

C28H40O
Purity

>98% (HPLC)
Solubility

DMSO : 20 mg/mL (50.94 mM; ultraphonic; )
SMILES

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Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gan KH, et al. Steroidal constituents of ganoderma applanatum and ganodermaneo-japonicum. J Nat Prod. 1998 Nov;61(11):1421-2.?

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