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(22E)-Ergosta-4,6,8(14),22-tetraen-3-one

CAS No. 19254-69-4

(22E)-Ergosta-4,6,8(14),22-tetraen-3-one( ——— )

Catalog No. M39405 CAS No. 19254-69-4

Ergosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (22E)-Ergosta-4,6,8(14),22-tetraen-3-one
  • Note
    Research use only, not for human use.
  • Brief Description
    Ergosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum.
  • Description
    Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment.
  • In Vitro
    ———
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Angiogenesis
  • Target
    Bcl-2
  • Recptor
    Bcl-2; p53; Caspase
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    19254-69-4
  • Formula Weight
    392.62
  • Molecular Formula
    C28H40O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 20 mg/mL (50.94 mM; ultraphonic; )
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gan KH, et al. Steroidal constituents of ganoderma applanatum and ganodermaneo-japonicum. J Nat Prod. 1998 Nov;61(11):1421-2.?
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