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T-155535

CAS No. 925001-05-4

T-155535( T155535 )

Catalog No. M16627 CAS No. 925001-05-4

T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

T-155535
Note

Research use only, not for human use.
Brief Description

T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay.
Description

T-155535 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 21 uM in AlphaScreen assay; displays 2.8-fold and 5.2-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.
In Vitro

——
In Vivo

——
Synonyms

T155535
Pathway

Wnt/Notch/Hedgehog
Target

Beta-catenin
Recptor

Beta-catenin
Research Area

——
Indication

——

Chemical Information

CAS Number

925001-05-4
Formula Weight

315.709
Molecular Formula

C16H10ClNO4
Purity

>98% (HPLC)
Solubility

——
SMILES

C1=CC(=CC=C1C2=CC(=NO2)C(=O)O)OC3=CC=C(C=C3)Cl
Chemical Name

5-(4-(4-chlorophenoxy)phenyl)isoxazole-3-carboxylic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

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