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Home - Products - Wnt/Notch/Hedgehog - Beta-catenin - FH535

FH535

CAS No. 108409-83-2

FH535( FH 535 | FH-535 )

Catalog No. M10331 CAS No. 108409-83-2

A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 29 In Stock
10MG 47 In Stock
25MG 86 In Stock
50MG 150 In Stock
100MG 259 In Stock
200MG 383 In Stock
500MG 619 In Stock
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Biological Information

  • Product Name
    FH535
  • Note
    Research use only, not for human use.
  • Brief Description
    A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment.
  • Description
    A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment; antagonizes β-catenin/Tcf–mediated transcription and inhibits the Wnt/β-catenin pathway; shows antiproliferation effect on transformed colon lung and liver cell lines.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FH 535 | FH-535
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Beta-catenin
  • Recptor
    PPARγ|PPARδ|Wnt/β-catenin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    108409-83-2
  • Formula Weight
    361.2005
  • Molecular Formula
    C13H10Cl2N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C([N+]([O-])=O)C=C2C)=O
  • Chemical Name
    Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Handeli S, et al. Mol Cancer Ther. 2008 Mar;7(3):521-9. 2. Gedaly R, et al. PLoS One. 2014 Jun 18;9(6):e99272. 3. Su H, et al. J Transl Med. 2015 Mar 31;13:104.
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