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Rev1-IN-5
CAS No. 908510-73-6
Rev1-IN-5( —— )
Catalog No. M16530 CAS No. 908510-73-6
Rev1-IN-5 is a small molecule inhibitor of the C-terminal domain of Rev1 and the Rev1-interacting region protein-protein interaction (Rev1-CT/RIR PPI) with IC50 of 2.5 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRev1-IN-5
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NoteResearch use only, not for human use.
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Brief DescriptionRev1-IN-5 is a small molecule inhibitor of the C-terminal domain of Rev1 and the Rev1-interacting region protein-protein interaction (Rev1-CT/RIR PPI) with IC50 of 2.5 uM.
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DescriptionRev1-IN-5 is a small molecule inhibitor of the C-terminal domain of Rev1 and the Rev1-interacting region protein-protein interaction (Rev1-CT/RIR PPI) with IC50 of 2.5 uM; binds to Rev1-CT at the RIR interface, inhibits mutagenic Rev1/Polζ-dependent translesion synthesis (TLS) in mouse embryonic fibroblasts and human fibrosarcoma HT1080 cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA Repair Protein
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RecptorDNA Repair Protein
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Research Area——
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Indication——
Chemical Information
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CAS Number908510-73-6
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Formula Weight403.541
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Molecular FormulaC21H29N3O3S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name1-acetyl-N-(3-(cyclopropylcarbamoyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)piperidine-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sail V, et al. ACS Chem Biol. 2017 Jul 21;12(7):1903-1912.
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