Cart
sales@molnova.com
Blebbistatin S enantiomer
CAS No. 856925-71-8
Blebbistatin S enantiomer( S)-(-)-Blebbistatin )
Catalog No. M16215 CAS No. 856925-71-8
Blebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 33 | In Stock |
|
| 5MG | 55 | In Stock |
|
| 10MG | 88 | In Stock |
|
| 25MG | 177 | In Stock |
|
| 100MG | 472 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBlebbistatin S enantiomer
-
NoteResearch use only, not for human use.
-
Brief DescriptionBlebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin.
-
DescriptionBlebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin, which is a potent and selective myosin II inhibitor with IC50 of 0.5-5 uM; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly, inhibits pancreatic adenocarcinoma cellular invasiveness; inhibits some myosin II-independent processes and that blebbistatin inhibits other activities in the absence of myosin II.
-
In Vitro——
-
In Vivo——
-
SynonymsS)-(-)-Blebbistatin
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMyosin
-
Recptornon-musclemyosinIIATPases
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number856925-71-8
-
Formula Weight292.3318
-
Molecular FormulaC18H16N2O2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 5.2 mg/mL (Need ultrasonic and warming)
-
SMILESCC1=CC2=C(C=C1)N=C3[C@](C2=O)(CCN3C4=CC=CC=C4)O
-
Chemical Name4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Straight AF, et al. Science. 2003 Mar 14;299(5613):1743-7.
2. Abe M, et al. J Biol Chem. 2003 Nov 28;278(48):47707-12.
3. Duxbury MS, et al. Biochem Biophys Res Commun. 2004 Jan 23;313(4):992-7.
4. Shu S, et al. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1472-7.
molnova catalog
related products
-
Myokinasib
Myokinasib is a mixed-type, selective inhibitor of Myosin Light Chain Kinase 1 (MLCK1) with IC50 of 7.9 uM.
-
JB002
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
-
ML-9 hydrochloride
ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM.
