Cart
sales@molnova.com
ML-9 hydrochloride
CAS No. 105637-50-1
ML-9 hydrochloride( ML9 | ML-9 | ML 9 )
Catalog No. M10258 CAS No. 105637-50-1
ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 35 | In Stock |
|
| 5MG | 32 | In Stock |
|
| 10MG | 49 | In Stock |
|
| 25MG | 92 | In Stock |
|
| 50MG | 133 | In Stock |
|
| 100MG | 198 | In Stock |
|
| 200MG | 324 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML-9 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM.
-
DescriptionML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM, inhibits Store-operated Ca2+ entry (SOCE) in a variety of cell lines; also inhibits PKA and PKC with Ki of 32 and 54 uM; inhibits STIM1-plasma membrane interactions and inhibits TRPC6 channels via a mechanism independent of inhibition of MLCK activity.
-
In Vitro——
-
In Vivo——
-
SynonymsML9 | ML-9 | ML 9
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMyosin
-
RecptorMyosin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number105637-50-1
-
Formula Weight361.281
-
Molecular FormulaC15H18Cl2N2O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 83.33 mg/mL (230.65 mM)
-
SMILESO=S(N1CCNCCC1)(C2=C3C=CC=C(Cl)C3=CC=C2)=O.[H]Cl
-
Chemical Name1-[(5-chloro-1-naphthalenyl)sulfonyl]hexahydro-1H-1,4-diazepine, monohydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Shi J, et al. Br J Pharmacol. 2007 Sep;152(1):122-31.
2. Várnai P, et al. Trends Pharmacol Sci. 2009 Mar;30(3):118-28.
3. Ito S, et al. Eur J Pharmacol. 2004 Feb 23;486(3):325-33.
molnova catalog
related products
-
Phenamacril
JS399-19 is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum. JS399-19 is a specific Fusarium myosin I inhibitor.
-
JB062
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively.
-
Myosin V-IN-1
Myosin V-IN-1 is a potent and selective inhibitor of Myosin V with a Ki value of 6 μM.Myosin V-IN-1 inhibits actin V and slows down actin-activated myosin V ATPase by selectively inhibiting the release of ADP from the actinoglobulin complex.
