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ANA975

CAS No. 847453-47-8

ANA975( ANA 975 )

Catalog No. M16149 CAS No. 847453-47-8

ANA975 is an oral prodrug of the TLR-7 agonist Isatoribine (ANA245;7-Thia-8-oxoguanosine) against hepatitis C virus (HCV) infection.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ANA975
  • Note
    Research use only, not for human use.
  • Brief Description
    ANA975 is an oral prodrug of the TLR-7 agonist Isatoribine (ANA245;7-Thia-8-oxoguanosine) against hepatitis C virus (HCV) infection.
  • Description
    ANA975 is an oral prodrug of the TLR-7 agonist Isatoribine (ANA245;7-Thia-8-oxoguanosine) against hepatitis C virus (HCV) infection.HCV Infection Phase 1 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ANA 975
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    TLR
  • Research Area
    Infection
  • Indication
    HCV Infection

Chemical Information

  • CAS Number
    847453-47-8
  • Formula Weight
    384.363
  • Molecular Formula
    C14H16N4O7S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](N(C2=NC(N)=NC=C2S3)C3=O)O1
  • Chemical Name
    (2R,3R,4R,5R)-2-(5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xiang AX, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):635-40.
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