Riboflavin

Research use only, not for human use.

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables.

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.

Cell Viability Assay Cell Line:HL60 cells Concentration:5-10 μM Incubation Time:24 h Result:Didn't affect cell viability with no UV irradiation.Western Blot Analysis Cell Line:HL60 cells Concentration:5-50 μM Incubation Time:24 h Result:Increased the ratio Bax/Bcl2 and decreased the level of inhibitory apoptosis protein type 1 (IAP1).Caused overexpression of Fas and FasL.Decreased the expression of TNFR1 and TRADD at the concentration of 10-50 μM.Inhibited the cell survival relevant kinases phospho-JNK, phospho-MEK, phospho-ERK.Increased the expression of p21 and decreased the expression of PCNA, STATs 1 and STATs 2.

Animal Model:Swiss albino miceDosage:10 mg/kg Administration:Oral gavage (p.o.), dailyResult:Increased the growth rate of pregnant and newbron mice.Increased the percent conception and average litter size of pregnant mices.Improved the percent zinc absorption in male mices.Increased the levels of zinc and iron in organs in male and female mices.Increased the percent hemoglobin and the blood zinc value of female mices.Animal Model:Female Wistar rats Dosage:1-600 mg/kg Administration:Oral gavage (p.o.), one time Result:Reduced flinching behavior during phase 2 in formalin-injected mice by doses of 1-50 mg/kg.Produced a significant antihyperalgesic effect in carrageenan-injected mice by doses of 6.25-150 mg/kg.Reduced carrageenan-induced edema by doses of 50-150 mg/kg.

Riboflavin, Vitamin B2, Vitamin G | Lactoflavin

Metabolic Enzyme/Protease

Vitamin

VB2

Other Indications

——

83-88-5

376.37

C17H20N4O6

>98% (HPLC)

DMSO: 0.1 mg/mL (0.26 mM); Water; Ethanol: insoluble

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](CO)O)O)O

7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione

(-20℃)

With Ice Pack

≥ 2 years