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THS-044
CAS No. 62054-67-5
THS-044( THS044 | THS 044 )
Catalog No. M15349 CAS No. 62054-67-5
THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 237 | Get Quote |
|
| 10MG | 380 | Get Quote |
|
| 25MG | 620 | Get Quote |
|
| 50MG | 883 | Get Quote |
|
| 100MG | 1215 | Get Quote |
|
| 500MG | 2412 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTHS-044
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NoteResearch use only, not for human use.
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Brief DescriptionTHS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).
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DescriptionTHS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM); modulates the affinity of the HIF2α:ARNT PAS-B heterodimer in vitro.
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In Vitro——
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In Vivo——
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SynonymsTHS044 | THS 044
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PathwayAngiogenesis
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TargetHIF/HIF Prolyl-hydroxylase
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RecptorHIF/HIF Prolyl-hydroxylase
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number62054-67-5
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Formula Weight291.2265
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Molecular FormulaC11H12F3N3O3
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC1COCCN1NC2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-]
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Chemical Name4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Scheuermann TH, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5.
2. Motto I, et al. J Chem Inf Model. 2011 Nov 28;51(11):2868-81.
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