ZINC13466751

CAS No. 117953-17-0

ZINC13466751( —— )

Catalog No. M26522 CAS No. 117953-17-0

ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 102 In Stock
5MG 93 In Stock
10MG 155 In Stock
25MG 255 In Stock
50MG 345 In Stock
100MG 443 In Stock
200MG 617 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ZINC13466751
  • Note
    Research use only, not for human use.
  • Brief Description
    ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 μM).
  • Description
    ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    HIF/HIF Prolyl-hydroxylase
  • Recptor
    CYP2B6| CYP2C19
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    117953-17-0
  • Formula Weight
    363.421
  • Molecular Formula
    C20H21N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (137.59 mM)
  • SMILES
    CC1=NN(C(=O)\C1=N/Nc1ccc(cc1)N1CCOCC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vijayabhaskar V, Srivastava P, Rajagopal S. Breaking the sensitivity limitations of cytochrome P450 oxidation product: dansyl chloride derivatisation of 4-OH mephenytoin, a CYP2C19 metabolite and its application to in vitro CYP inhibition assay. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 May 1;989:27-36.
molnova catalog
related products
  • Dimethyloxaloylglyci...

    DMOG is an antagonist of α-ketoglutarate cofactor and inhibitor for HIF prolyl hydroxylase.

  • KHS-101

    KHS-101 (KHS101) is a small molecule that selectively induces a neuronal differentiation phenotype.

  • IOX 2

    IOX2 is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD).