Acitretin( all-trans Acitretin | Ro 10-1670 | Ro 10-1670/000 )

Catalog No. M14992 CAS No. 55079-83-9

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Acitretin
Note

Research use only, not for human use.
Brief Description

Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
Description

Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.(In Vivo):Acitretin (10 mg/kg; i.p. for 7 days) increases IL-6 in the central nervous system of Alzheimer’s disease model mice.
In Vitro

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In Vivo

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Synonyms

all-trans Acitretin | Ro 10-1670 | Ro 10-1670/000
Pathway

Metabolic Enzyme/Protease
Target

Retinoid Receptor
Recptor

RAR| RXR
Research Area

Inflammation/Immunology
Indication

——

CAS Number

55079-83-9
Formula Weight

326.43
Molecular Formula

C21H26O3
Purity

>98% (HPLC)
Solubility

DMSO: 20 mg/mL (61.26 mM)
SMILES

CC1=CC(=C(C(=C1C=CC(=CC=CC(=CC(=O)O)C)C)C)C)OC
Chemical Name

(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid

1.Orfanos CE, et al. Drugs. 1997 Mar;53(3):358-88.

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