Etonogestrel

Research use only, not for human use.

Etonogestrel is a steroidal progestin used in hormonal contraceptives.

Etonogestrel is a steroidal progestin used in hormonal contraceptives.(In Vitro):Etonogestrel inhibits fertility by inhibiting the release of luteinizing hormone (LH), one of the reproductive hormones important in ovulation.Etonogestrel also increases the viscosity of cervical mucus, which hinders the passage of spermatozoa and alters the lining of the uterus to prevent implantation of a fertilized egg into the endometrium.Etonogestrel, a progestin, is a substrate of the CYP 3A4 oxidase system.Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).

Etonogestrel inhibits fertility by inhibiting the release of luteinizing hormone (LH), one of the reproductive hormones important in ovulation.Etonogestrel also increases the viscosity of cervical mucus, which hinders the passage of spermatozoa and alters the lining of the uterus to prevent implantation of a fertilized egg into the endometrium.Etonogestrel, a progestin, is a substrate of the CYP 3A4 oxidase system.Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs). Western Blot AnalysisCell Line:Human endometrial stromal cells (HESCs) Concentration:100 nM Incubation Time:24 hoursResult:Increased FKBP51 mRNA and protein levels.

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ORG 3236 | 3-keto Desogestrel | 3-oxo Desogestrel

Endocrinology/Hormones

Estrogen Receptor/ERR

ER

Endocrinology

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54048-10-1

324.46

C22H28O2

>98% (HPLC)

DMSO: 10 mM

CC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34

(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

(-20℃)

With Ice Pack

≥ 2 years