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Allopregnanolone

CAS No. 516-54-1

Allopregnanolone( 3α,5α-THP | SAGE547 | SAGE 547 | SAGE-547 )

Catalog No. M14799 CAS No. 516-54-1

An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Allopregnanolone
  • Note
    Research use only, not for human use.
  • Brief Description
    An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
  • Description
    An endogenous inhibitory pregnane neurosteroid and potent positive allosteric modulator of GABAA receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    3α,5α-THP | SAGE547 | SAGE 547 | SAGE-547
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GABA
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    516-54-1
  • Formula Weight
    318.49346
  • Molecular Formula
    C21H34O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
  • Chemical Name
    Pregnan-20-one, 3-hydroxy-, (3α,5α)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Reddy DS, et al. Prog Brain Res. 2010;186:113-37. 2. Pinna G, et al. Neuropharmacology. 2000 Jan 28;39(3):440-8. 3. Kokate TG, et al. J Pharmacol Exp Ther. 1994 Sep;270(3):1223-9.
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