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SNAP 5114
CAS No. 157604-55-2
SNAP 5114( SNAP5114 | SNAP-5114 | (S)-SNAP 5114 )
Catalog No. M12251 CAS No. 157604-55-2
A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 45 | In Stock |
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| 5MG | 42 | In Stock |
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| 10MG | 67 | In Stock |
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| 25MG | 155 | In Stock |
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| 50MG | 220 | In Stock |
|
| 100MG | 319 | In Stock |
|
| 200MG | 436 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSNAP 5114
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NoteResearch use only, not for human use.
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Brief DescriptionA GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.
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DescriptionA GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively; increases thalamic GABA levels and is an anticonvulsant following systemic administration in vivo.
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In Vitro——
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In Vivo——
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SynonymsSNAP5114 | SNAP-5114 | (S)-SNAP 5114
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGAT
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Research Area——
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Indication——
Chemical Information
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CAS Number157604-55-2
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Formula Weight505.61
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Molecular FormulaC30H35NO6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (197.78 mM)
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SMILESO=C([C@@H]1CN(CCOC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)CCC1)O
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Chemical Name1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dhar TG, et al. J Med Chem. 1994 Jul 22;37(15):2334-42.
2. Christiansen B, et al. J Biol Chem. 2007 Jul 6;282(27):19331-41.
3. Doengi M, et al. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17570-5.
4. Dvorzhak A, et al. J Physiol. 2010 Jul 1;588(Pt 13):2351-60.
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