NVP-ADW742

CAS No. 475489-15-7

NVP-ADW742( —— )

Catalog No. M14584 CAS No. 475489-15-7

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NVP-ADW742
  • Note
    Research use only, not for human use.
  • Brief Description
    NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
  • Description
    NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    IGF-1R
  • Recptor
    IGF-1R
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    475489-15-7
  • Formula Weight
    453.38
  • Molecular Formula
    C28H31N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: > 10mM
  • SMILES
    NC1=NC=NC2=C1C(=CN2C1CC(CN2CCCC2)C1)C1=CC(OCC2=CC=CC=C2)=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mitsiades CS, et al. Y Cell, 2004, 5(3), 221-230.
molnova catalog
related products
  • KW-2450 free base

    KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity.

  • GIP (3-42), human

    GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.

  • CTLA-4 inhibitor

    CTLA-4 inhibitor is a potent CTLA-4 inhibitor.