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NVP-ADW742

CAS No. 475489-15-7

NVP-ADW742( —— )

Catalog No. M14584 CAS No. 475489-15-7

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

NVP-ADW742
Note

Research use only, not for human use.
Brief Description

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
Description

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

IGF-1R
Recptor

IGF-1R
Research Area

——
Indication

——

Chemical Information

CAS Number

475489-15-7
Formula Weight

453.38
Molecular Formula

C28H31N5O
Purity

>98% (HPLC)
Solubility

DMSO: > 10mM
SMILES

NC1=NC=NC2=C1C(=CN2C1CC(CN2CCCC2)C1)C1=CC(OCC2=CC=CC=C2)=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Mitsiades CS, et al. Y Cell, 2004, 5(3), 221-230.

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