KW-2450 free base

CAS No. 904899-25-8

KW-2450 free base( —— )

Catalog No. M36254 CAS No. 904899-25-8

KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 801 In Stock
5MG 1216 In Stock
10MG 1644 In Stock
25MG 2442 In Stock
50MG 3143 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KW-2450 free base
  • Note
    Research use only, not for human use.
  • Brief Description
    KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity.
  • Description
    KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    IGF-1R
  • Recptor
    IGF-1R
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    904899-25-8
  • Formula Weight
    515.63
  • Molecular Formula
    C28H29N5O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=C/C1=C(NC(=O)C=2SC=CC2C)C=C(CN3CCN(C(CO)=O)CC3)C=C1)\C=4C=5C(NN4)=CC=CC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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