HNMPA

CAS No. 132541-52-7

HNMPA( —— )

Catalog No. M27459 CAS No. 132541-52-7

HNMPA is an inhibitor of insulin receptor tyrosine kinase and inhibits the serine and tyrosine autophosphorylation of human insulin receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 53 Get Quote
5MG 77 Get Quote
10MG 132 Get Quote
25MG 285 Get Quote
50MG 428 Get Quote
100MG 626 Get Quote
500MG 1323 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    HNMPA
  • Note
    Research use only, not for human use.
  • Brief Description
    HNMPA is an inhibitor of insulin receptor tyrosine kinase and inhibits the serine and tyrosine autophosphorylation of human insulin receptor.
  • Description
    HNMPA is an inhibitor of insulin receptor tyrosine kinase and inhibits the serine and tyrosine autophosphorylation of human insulin receptor.(In Vitro):HNMPA reduces neuronal firing after GABA application and blocks GABA-dependent insulin inhibition. HNMPA has no effect on cyclic AMP-dependent protein kinase or protein kinase C activities.
  • In Vitro
    HNMPA inhibits the phosphorylation of a synthetic peptide substrate composed of insulin receptor residues 1290-1319 on serines-1305/1306 by partially purified insulin receptors.HNMPA blocks GABA-dependent insulin inhibition, and reduces neuronal firing after GABA application.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    IGF-1R
  • Recptor
    DNMT3B|Parasite|antimalarial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    132541-52-7
  • Formula Weight
    238.18
  • Molecular Formula
    C11H11O4P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=P(O)(O)C(O)C=1C=CC=2C=CC=CC2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tanaka Y, et al.Heme-dependent radical generation: possible involvement in antimalarial action of non-peroxide microbial metabolites, nanaomycin A and radicicol.J Antibiot (Tokyo). 1999 Oct;52(10):880-8.
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