Lithocholic acid( 3α-hydroxy Cholanic Acid | LCA | Lithocholate | NSC 683770 )

Catalog No. M14480 CAS No. 434-13-9

COA

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HNMR

HPLC

MSDS

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Product Name

Lithocholic acid
Note

Research use only, not for human use.
Brief Description

Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.
Description

Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.
In Vitro

——
In Vivo

——
Synonyms

3α-hydroxy Cholanic Acid | LCA | Lithocholate | NSC 683770
Pathway

Metabolic Enzyme/Protease
Target

FXR
Recptor

FXR| PXR| VD
Research Area

Metabolic Disease
Indication

——

CAS Number

434-13-9
Formula Weight

376.58
Molecular Formula

C24H40O3
Purity

>98% (HPLC)
Solubility

Ethanol: 47 mg/mL (124.81 mM); DMSO: 75 mg/mL (199.16 mM)
SMILES

C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Chemical Name

3alpha-Hydroxy-5beta-cholan-24-oic acid

1.Kozoni V, et al. Carcinogenesis. 2000 May;21(5):999-1005.

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