Glucosamine

CAS No. 3416-24-8

Glucosamine( —— )

Catalog No. M14160 CAS No. 3416-24-8

Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Glucosamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
  • Description
    Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies. It is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis. (In Vitro):Glucosamine (D-Glucosamine) exhibits dose-dependent DPPH antioxidant activity.Glucosamine treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins.Glucosamine significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.
  • In Vitro
    Glucosamine (D-Glucosamine) exhibits dose-dependent DPPH antioxidant activity. Glucosamine treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins. Glucosamine significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    Chitosanase| MMP-9| NF-κB| IFγ| TNF-α
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    3416-24-8
  • Formula Weight
    179.17
  • Molecular Formula
    C6H13NO5
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 551.0 mg/mL
  • SMILES
    NC(C=O)C(O)C(O)C(O)CO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fenton JI, et al. Equine Vet J Suppl. 2002 Sep;(34):219-23.
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