Triclosan

Research use only, not for human use.

Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments.

Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments.

Cell Viability AssayCell Line:Neural stem wells Concentration:1, 10, 20, 30, 50 and 100 μM Incubation Time:24 h Result:Initiated the decreases in cell viability in dose and time dependent manners with 50 and 100 μM. Differentially induced the increased expressions of both phosphorylated p38 and JNK proteins.

Animal Model:Wild type BALB/cJ mice Dosage:5, 50, 500 mg/kg Administration:Oral gavage, five days a week for a total of four weeks Result:Caused an increase in the production of anti- dermatophagoides farinae (Der f) IgE, IL‐4, and IL‐13, and this resulted in the aggravation of airway hyperresponsiveness in aeroallergen‐exposed wild type mice.

Triclosan

Membrane Transporter/Ion Channel

NADPH

NADPH

Infection

——

3380-34-5

289.54

C12H7Cl3O2

>98% (HPLC)

DMSO: > 10 mM

OC1=CC(Cl)=CC=C1OC2=CC=C(Cl)C=C2Cl

2,4,4'-Trichloro-2'-hydroxy diphenyl ether

(-20℃)

With Ice Pack

≥ 2 years