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Obafistat

CAS No. 2160582-57-8

Obafistat( —— )

Catalog No. M28228 CAS No. 2160582-57-8

Obafistat is a potent aldo-keto reductase AKR1C3 inhibitor with an IC 50 of 1.2 nM for human AKR1C3 .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
2MG 45 In Stock
5MG 73 In Stock
10MG 113 In Stock
25MG 188 In Stock
50MG 300 In Stock
100MG 485 In Stock
200MG 668 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Obafistat
  • Note
    Research use only, not for human use.
  • Brief Description
    Obafistat is a potent aldo-keto reductase AKR1C3 inhibitor with an IC 50 of 1.2 nM for human AKR1C3 .
  • Description
    Obafistat is a potent aldo-keto reductase AKR1C3 inhibitor with an IC 50 of 1.2 nM for human AKR1C3 .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    NADPH
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2160582-57-8
  • Formula Weight
    365.38
  • Molecular Formula
    C15H16FN5O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (171.05 mM)
  • SMILES
    O=C(c1cnn[nH]1)N(CC1CC2)CC2N1S(c1cc(F)ccc1)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402.
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