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NKY80
CAS No. 299442-43-6
NKY80( NKY 80 | NKY-80 )
Catalog No. M13924 CAS No. 299442-43-6
A potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | Get Quote |
|
| 5MG | 56 | Get Quote |
|
| 10MG | 87 | Get Quote |
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| 25MG | 177 | Get Quote |
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| 50MG | 309 | Get Quote |
|
| 100MG | 471 | Get Quote |
|
| 200MG | 678 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNKY80
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively.
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DescriptionA potent, selective adenylyl cyclase AC5/6 inhibitor with IC50 of 7.7/17 uM, respectively; displays little to no activity for other AC isoforms (IC50>100 uM); blocks both BAPTA-AM-stimulated cAMP formation and renin release in primary cultures of juxtaglomerular cells.
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In Vitro——
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In Vivo——
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SynonymsNKY 80 | NKY-80
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PathwayMetabolic Enzyme/Protease
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TargetAdenylate Cyclase
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RecptorAdenylate Cyclase
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Research Area——
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Indication——
Chemical Information
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CAS Number299442-43-6
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Formula Weight229.239
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Molecular FormulaC12H11N3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1090.61 mM)
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SMILESO=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1
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Chemical Name2-amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Onda T, et al. J Biol Chem. 2001 Dec 21;276(51):47785-93.
2. Ortiz-Capisano MC, et al. Hypertension. 2007 Mar;49(3):618-24.
3. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.
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