Methoxsalen

Research use only, not for human use.

A potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight.

A potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight; inhibits human CYP2A6 and mouse CYP2A5, inhibits nicotine metabolism and alters the behavioral effects of nicotine in the mouse; also induces Ca2+ entry in MG63 human osteosarcoma cells.Blood Cancer Approved.

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Animal Model:Male adult ICR mice Dosage:15 mg/kg Administration:Intraperitoneal injection (i.p.), single dose Result:Increased nicotine plasma levels were still above 10ng/ml at 6hr.Induced nicotine’s antinociceptive and hypothermic lasted close to 6 and 24 hr.

8-Methoxypsoralen | Xanthotoxin | 8-MOP

Metabolic Enzyme/Protease

CYPs

DNA

Cancer

Blood cancer

298-81-7

216.1895

C12H8O4

>98% (HPLC)

10 mM in DMSO

O=C1C=CC2=CC3=C(OC=C3)C(OC)=C2O1

7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-

(-20℃)

With Ice Pack

≥ 2 years